bcl-2(124), Alkaline Phosphatase conjugate, 0.1mg/mL

Shipped by OZYME

Type SKU Price HT Quantity
  • 500 μl
BTMBNCAP0530-500
  • 100 μl
BTMBNCAP0530-100

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General Information
Description

This antibody recognizes a protein of 25-26 kDa, identified as the bcl-2 α oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of bcl-2 α oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of bcl-2 α protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. See the CF® Dye Selection Guide for more information. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Stock status: Because Biotium offers a large number of antibody and conjugation options, primary antibody conjugates may be made to order. Typical lead times are up to one week for CF® dye and biotin conjugates, and up to 2-3 weeks for fluorescent protein and enzyme conjugates. Please email order@biotium.com to inquire about stock status and lead times before placing your order.
  Catalog number key for antibody number 0530, Anti-Bcl-2 (124) [table id=253 /]

Product Information

Purchasing Information
Certification RUO
French code (NACRES) NA.45
UNSPSC code 41105331
EU customs code 30021010
Human origin No
Target Details
MW target protein (kDa) 25-26 kDa
Identification
NCBI (gene ID) 596
Brand
Brand Biotium
Product properties
Supplier category 1 Primary
Clonality Monoclonal
Clone 124
Concentration 0.1 mg/mL
Conjugate / tag Alkaline phosphatase
Host Mouse
Immunogen A synthetic peptide, aa41-54 (GAAPAPGIFSSQPG-Cys) of human Bcl-2 protein.
Isotype (antibody class) IgG1, kappa
Technical presentation https://biotium.com/product/monoclonal-anti-bcl-2-124
Validated reactivity Human
Usage
Shelf-Life (months) 24
Shipping temperature Room temperature
Dilution for application Does not react with mouse or rat, others not known
Storage temperature 2-8°C
Applications FC (FACS) , IF (ImmunoFluorescence) , IHC-Paraffin (paraffin tissues) , WB (Western Blot)
Research area Apoptosis

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