Type SKU Price HT Quantity
  • 100 μg
Contact us
BLE344720

You have not filled quantity

A wishlist already exists with this name

Variants without price will not be added to cart

General Information
Description

CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α 3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

Product Information

Purchasing Information
Certification RUO
French code (NACRES) NA.44
UNSPSC code 41116015
Country of origin (manufacturing) US
Delivery time 1
EU customs code 30021010
Vendor country US
Human origin No
Target Details
Other names T8 , Leu2
Identification
NCBI (gene ID) 925
Brand
Brand Biolegend
Product properties
Supplier category 4 FLOW
Supplier category 3 Biotin
Supplier category 2 BIOTIN
Supplier category 1 Human Immunology
Marketing brochures https://yris.ozyme.fr/ble-brochure
Videos - tutorials https://www.biolegend.com/fr-fr/video-library
MSDS https://www.biolegend.com/fr-fr/sds
Datasheet/manual https://www.biolegend.com/fr-fr/technical-protocols
Cross-reactivity African Green , Chimpanzee , Cynomolgus , Pigtailed Macaque , Rhesus , Sooty Mangabey
Clonality Monoclonal
Clone SK1
Concentration 0,5 mg/ml
Conjugate / tag Biotine
Host Mouse
Isotype (antibody class) IgG1, κ
Technical presentation https://www.biolegend.com/Default.aspx?ID=10267&productid=6510
Validated reactivity Human
Recombinant antibodies No
Scientific Articles & Reviews
Citations https://www.biolegend.com/fr-fr/publications-library
Customers reviews https://www.biolegend.com/fr-fr/reviews-library
Usage
Shelf-Life (months) 84
Shipping temperature Room T°
Storage temperature +4°C
Applications FC (FACS)
Clone:
RPA-T8
Conjugate / tag:
Biotin
Validated reactivity:
Human
Applications:
FC (FACS)

You have not filled quantity

Clone:
SK1
Conjugate / tag:
Biotin
Validated reactivity:
Human
Applications:
FC (FACS)

You have not filled quantity

List of all reviews