CD104(UM-A9), CF680R conjugate, 0.1mg/mL

Shipped by OZYME

Type SKU Price HT Quantity
  • 500 μl
BTMBNC810449-500
  • 100 μl
BTMBNC810449-100

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General Information
Description

Recognizes a protein of 205 kDa, which is identified as integrin beta-4 (ITGB4). Its epitope is localized in the extracellular domain of ITGB4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta-4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. See the CF® Dye Selection Guide for more information. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Stock status: Because Biotium offers a large number of antibody and conjugation options, primary antibody conjugates may be made to order. Typical lead times are up to one week for CF® dye and biotin conjugates, and up to 2-3 weeks for fluorescent protein and enzyme conjugates. Please email order@biotium.com to inquire about stock status and lead times before placing your order.
Catalog number key for antibody number 0449, Anti-CD104 (UM-A9)Â [table id=253 /]

Product Information

Purchasing Information
Certification RUO
French code (NACRES) NA.44
UNSPSC code 41105331
EU customs code 30021010
Human origin No
Target Details
MW target protein (kDa) 205 kDa
Identification
NCBI (gene ID) 3691
Brand
Brand Biotium
Product properties
Supplier category 1 Primary
Clonality Monoclonal
Clone UM-A9
Concentration 0.1 mg/mL
Conjugate / tag CF680R
Host Mouse
Immunogen Human squamous cell carcinoma (UM-SCC1)
Isotype (antibody class) IgG2a, kappa
Technical presentation https://biotium.com/product/monoclonal-anti-cd104-um-a9
Validated reactivity Human
Usage
Shelf-Life (months) 24
Shipping temperature Room temperature
Dilution for application Biological blockade partially blocks laminin binding
Storage temperature 2-8°C
Applications Receptor blockade , FC (FACS) , IF (ImmunoFluorescence)
Research area Cancer

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