CD1a(O10), APC conjugate, 0.1mg/mL

Shipped by OZYME

Type SKU Price HT Quantity
  • 250 μl
BTMBNCA0667-250

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General Information
Description At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa). Primary antibodies are available purified, or with a selection of fluorescent CF&reg; dyes and other labels. CF&reg; dyes offer exceptional brightness and photostability. See the <a href="https://biotium.com/wp-content/uploads/2013/07/CF-Dye-Brochure.pdf" target="_blank" rel="noopener">CF&reg; Dye Selection Guide</a> for more information. Note: Conjugates of blue fluorescent dyes like CF&reg;405S and CF&reg;405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.<div><strong>Stock status:</strong> Because Biotium offers a large number of antibody and conjugation options, primary antibody conjugates may be made to order. Typical lead times are up to one week for CF® dye and biotin conjugates, and up to 2-3 weeks for fluorescent protein and enzyme conjugates. Please email <a href="mailto:order@biotium.com">order@biotium.com</a> to inquire about stock status and lead times before placing your order.</div>&nbsp; <strong>Catalog number key for antibody number 0667, Anti-CD1a (O10)</strong>&nbsp;[table id=253 /]

Product Information

Purchasing Information
Certification RUO
French code (NACRES) NA.44
UNSPSC code 41105331
Human origin No
Target Details
MW target protein (kDa) 49 kDa
Identification
NCBI (gene ID) 909
Brand
Brand Biotium
Product properties
Supplier category 1 Primary
Clonality Monoclonal
Clone O10
Concentration 0.1 mg/mL
Conjugate / tag APC
Host Mouse
Immunogen Human thymus cells
Isotype (antibody class) IgG1, kappa
Validated reactivity Human
Technical presentation https://biotium.com/product/monoclonal-anti-cd1a-o10
Usage
Shelf-Life (months) 24
Shipping temperature Room temperature
Dilution for application Immunohistology formalin-fixed 0.5-1 ug/mL
Storage temperature 2 - 8 °C
Applications IF (ImmunoFluorescence) , IHC-Paraffin (paraffin tissues) , FC (FACS)
Research area Cancer

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