CORIN Polyclonal Antibody (CAB10404)

OverviewTitle:CORIN Polyclonal Antibody (CAB10404)Size:100 μLCode:CAB10404Host Species:RabbitPurification:Affinity purificationIsotype:IgGBackgroundThis gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Immunogen InformationImmunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human CORIN (NP_006578.2).GeneID:10699SwissProt:Q9Y5Q5Synonyms:CORIN; ATC2; CRN; Lrp4; PEE5; TMPRSS10; corin, serine peptidaseCalculated MW:113kDa/116kDaObserved MW:116kDaApplicationsReactivity:Human, Mouse, RatTested Applications:WBRecommended Dilution:WB 1:500 - 1:2000Storage Buffer:Store at -20 °C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.Application Key:Western blotting Positive Samples:Hela, HT-1080, Mouse heart, Mouse brain, Rat heart, Rat brainCellular Location:Cell membrane, Secreted, Single-pass type II membrane protein, Single-pass type II membrane proteinAntibody ImagesWestern blot analysis of extracts of various cell lines, using CORIN antibody (CAB10404) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s. Datasheets