Cytokeratin 8(H1), CF680R conjugate, 0.1mg/mL

Expédié par OZYME

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  • 500 μl
  • 100 μl

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General Information
Description Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19). Reportedly, anti-CK8 is useful for the differentiation of lobular ( ring-like, perinuclear ) from ductal ( peripheral-predominant ) carcinoma of the breast. Primary antibodies are available purified, or with a selection of fluorescent CF&reg; dyes and other labels. CF&reg; dyes offer exceptional brightness and photostability. See the <a href="" target="_blank" rel="noopener">CF&reg; Dye Selection Guide</a> for more information. Note: Conjugates of blue fluorescent dyes like CF&reg;405S and CF&reg;405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.<div><strong>Stock status:</strong> Because Biotium offers a large number of antibody and conjugation options, primary antibody conjugates may be made to order. Typical lead times are up to one week for CF® dye and biotin conjugates, and up to 2-3 weeks for fluorescent protein and enzyme conjugates. Please email <a href=""></a> to inquire about stock status and lead times before placing your order.</div>&nbsp; <strong>Catalog number key for antibody number 0334, Anti-Cytokeratin 8 (H1)</strong>&nbsp;[table id=253 /]

Product Information

Purchasing Information
Certification RUO
French code (NACRES) NA.44
UNSPSC code 41105331
Human origin No
Target Details
MW target protein (kDa) 52.5 kDa
NCBI (gene ID) 3856
Brand Biotium
Product properties
Supplier category 1 Primary
Clonality Monoclonal
Clone H1
Concentration 0.1 mg/mL
Conjugate / tag CF680R
Host Mouse
Immunogen Cytoskeleton preparation containing cytokeratin 8
Isotype (antibody class) IgG1
Validated reactivity Human , Rat
Technical presentation
Shelf-life (months) 24
Shipping temperature Room temperature
Dilution for application Immunohistology formalin-fixed 1-2 ug/mL
Storage temperature 2 - 8 °C
Applications IF (ImmunoFluorescence) , IHC-Paraffin (paraffin tissues) , FC (FACS)
Research area Cancer

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