Plasma Cell Marker(LIV3G11 (7B18)), 0.2mg/mL

Expédié par OZYME

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Type SKU Price HT Quantity
  • 500 μl
BTMBNUB0047-500
  • 100 μl
BTMBNUB0047-100

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General Information
Description This antibody recognizes an intra-cytoplasmic antigen, which shows a very high degree of specificity for plasma cells. This antigen is present in normal as well as neoplastic plasma cells. Plasma cells, which are large lymphocytes derived from an antigen-specific B cell, secrete antibodies and are responsible for humoral immunity. Plasma cells differentiate from B cells upon stimulation by CD4 lymphocytes. The B cell acts as an antigen-presenting cell (APC), consuming an offending pathogen, which is taken up by the B cell by phagocytosis and broken down within proteosomes. Plasma cells contain basophilic cytoplasm; their nucleus contains heterochromatin organized in a characteristic cartwheel arrangement. This MAb superbly recognizes normal and neoplastic plasma cells in routine formalin-fixed, paraffin-embedded tissue sections. It is of potential value in identifying myeloma or plasmacytoma in bone marrow or other tissues. It also helps differentiate lympho-plasmacytoid lymphoma from lymphocytic and follicular lymphoma. Note that this MAb is not suitable for staining frozen tissues. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. See the <a href="https://biotium.com/wp-content/uploads/2013/07/CF-Dye-Brochure.pdf" target="_blank" rel="noopener">CF® Dye Selection Guide</a> for more information. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.<div><strong>Stock status:</strong> Because Biotium offers a large number of antibody and conjugation options, primary antibody conjugates may be made to order. Typical lead times are up to one week for CF® dye and biotin conjugates, and up to 2-3 weeks for fluorescent protein and enzyme conjugates. Please email <a href="mailto:order@biotium.com">order@biotium.com</a> to inquire about stock status and lead times before placing your order.</div>&nbsp; <strong>Catalog number key for antibody number 0047, Anti-Plasma Cell Marker (LIV3G11; same as 7B18)</strong>&nbsp;[table id=253 /]

Product Information

Purchasing Information
Certification RUO
French code (NACRES) NA.41
UNSPSC code 41105331
Human origin No
Target Details
MW target protein (kDa) Not Known
Brand
Brand Biotium
Product properties
Supplier category 1 Primary
Clonality Monoclonal
Clone LIV3G11
Concentration 0.2 mg/mL
Conjugate / tag Purified, with BSA
Host Mouse
Immunogen Pancreatic cancer-related mucin
Isotype (antibody class) IgG2a
Validated reactivity Human
Technical presentation https://biotium.com/product/monoclonal-anti-plasma-cell-marker-liv3g11-7b18
Usage
Shelf-life (months) 24
Shipping temperature Room temperature
Dilution for application Does not react with rat
Storage temperature 2 - 8 °C
Applications IHC-Paraffin (paraffin tissues)
Research area Immunology

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