Purified anti-human CD254 (TRANCE, RANKL)

Shipped by OZYME

Type SKU Price HT Quantity
  • 25 μg

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General Information
Description Human CD254, also known as RANKL, TRANCE, and OPGL, is a type II transmembrane protein in the TNF superfamily that has two forms: a membrane-anchored protein and a secreted protein. Its extracellular domain is related to TRAIL, FasL, and TNF. CD254 is expressed on osteoblasts and activated T cells. It has been implicated in the regulation of the interactions between T cells and dendritic cells. It plays an important role in osteoblast differentiation and bone resorption. CD254 activates JNK and NF-κB and induces the expression of IL-1, IL-6, IL-12, and IL-15 in dendritic cells.

Product Information

Purchasing Information
Certification RUO
French code (NACRES) NA.41
UNSPSC code 41116015
Delivery time 1
Country of origin (manufacturing) US
EU customs code 30021010
Vendor country US
Human origin No
Target Details
Other names TRANCE (TNF-related activation-induced cytokine receptor) , CD254 , RANK-L (receptor activator of NF-κB ligand) , OPGL (Osteoprotegerin ligand) , SOFA , TNFSF-11
NCBI (gene ID) 8600
Brand Biolegend
Product properties
Supplier category 1 Human Immunology
Supplier category 2 PURE
Supplier category 3 PURE
Supplier category 4 FLOW
Datasheet/manual https://www.biolegend.com/fr-fr/technical-protocols
MSDS https://www.biolegend.com/fr-fr/sds
Marketing brochures https://yris.ozyme.fr/ble-brochure
Videos - tutorials https://www.biolegend.com/fr-fr/video-library
Clonality Monoclonal
Clone MIH24
Concentration 0,5 mg/ml
Conjugate / tag non couplé
Host Mouse
Immunogen RANKL-transfected L cells
Isotype (antibody class) IgG2b, κ
Validated reactivity Human
Technical presentation https://www.biolegend.com/Default.aspx?ID=10267&productid=6396
Recombinant antibodies No
Scientific Articles & Reviews
Citations https://www.biolegend.com/fr-fr/publications-library
Customers reviews https://www.biolegend.com/fr-fr/reviews-library
Shelf-Life (months) 120
Shipping temperature Room T°
Storage temperature +4°C
Applications FC (FACS) , ELISA , IHC-Paraffin (paraffin tissues)

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