Recombinant Human IL-9 (ELISA Std.)

Shipped by OZYME

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General Information

IL-9 was initially identified in mice as a T cell growth factor. Human and murine IL-9 show a 56% amino acid sequence homology. IL-9 is a cytokine that acts as a regulator of a variety of hematopoietic cells, stimulates cell proliferation, and prevents apoptosis. The IL-9 receptor consists of the cytokine-specific IL-9 receptor α-chain (IL-9Rα) and the common γ-chain that is shared by IL-2, IL-4, IL-7, IL-15, and IL-21. IL-9 is expressed by activated Th9, Th17, Tregs, and mast cells and appears to play an important role in the development and function of subsets within the CD4 + T cell lineage. IL-9 also inhibits immune responses by enhancing the suppressive properties of Tregs and by recruiting immunosuppressive mast cells to sites of inflammation. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a key factor in the pathogenesis of bronchial hyperresponsiveness. In this sense, it has been described that IL-9 and IL-9R expression are increased in lungs of asthmatic patients. In addition, IL-9 promotes mast cell mediated intestinal permeability and plays a role in the development of food allergies. IL-9 has also been associated with atopic dermatitis.

Product Information

Purchasing Information
Certification RUO
French code (NACRES) NA.77
UNSPSC code 12352202
Country of origin (manufacturing) US
Delivery time 1
EU customs code 30021010
Vendor country US
Human origin No
Target Details
Other names TCGF-3 , MCGF , P40 , Interleukin-9
NCBI (gene ID) 16198
Brand Biolegend
Product properties
Marketing brochures
Supplier category 4 BMIA
Supplier category 3 RECOM
Supplier category 2 RECOM_STANDARD
Videos - tutorials
Conjugate / tag RECOM_STANDARD
Concentration lot-specific
Product presentation
Supplier category 1 Recombinant Protein
Recombinant antibodies No
Host Rat
Technical presentation
Scientific Articles & Reviews
Customers reviews
Shelf-Life (months) 60
Shipping temperature Room T°
Storage temperature +4°C
Applications ELISA

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