- General Information
- Purchasing Information
- Target Details
- Identification
- Brand
- Product properties
- Usage
- Alternative products
| General Information | |
|---|---|
| Description | This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. Epitope of this MAb is mapped between aa300-550. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. See the CF® Dye Selection Guide for more information. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. |
Informations produit
| Purchasing Information | |
|---|---|
| Certification | RUO |
| French code (NACRES) | NA.44 |
| UNSPSC code | 41105331 |
| EU customs code | 30021010 |
| Human origin | No |
| Target Details | |
|---|---|
| MW target protein (kDa) | 67 kDa |
| Identification | |
|---|---|
| NCBI (gene ID) | 2099 |
| Brand | |
|---|---|
| Brand | Biotium |
| Product properties | |
|---|---|
| Supplier category 1 | Primary |
| Clonality | Monoclonal |
| Clone | ESR1/420 |
| Concentration | 0.1 mg/mL |
| Conjugate / tag | CF594 |
| Host | Mouse |
| Immunogen | Recombinant human ESR1 protein (aa290-560) |
| isotype (antibody class) | IgG2a |
| Technical presentation | https://biotium.com/product/monoclonal-anti-estrogen-receptor-esr1420 |
| Validated reactivity | Human |
| Usage | |
|---|---|
| Shelf-Life (months) | 24 |
| Shipping temperature | Room temperature |
| Dilution for application | Flow Cytometry 0.5-1 ug/million cells/0.1 mL |
| Storage temperature | 2-8°C |
| Applications | FC (FACS) , IF (ImmunoFluorescence) , WB (Western Blot) |
| Research area | Cancer |