- General Information
- Purchasing Information
- Target Details
- Brand
- Product properties
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- Alternative products
General Information | |
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Description | This MAb is specific for progesterone. It exhibits minimal cross reactivity with related compounds in ELISA. It reacts with Progesterone-11a-HMS-BSA: 100%; 5-beta-Pregnane-3,20-dione: 48%; 5-alpha-Pregnane-3,20-dione: 26.4%; 17-alpha-Hydroxyprogesterone: 2.5%; 20-alpha-Hydroxyprogesterone: 0.04%. Progesterone is a steroid hormone synthesized from the cholesterol derivative, pregnenolone, in the cortex of the adrenal gland. Progesterone is secreted by the corpus luteum and acts to prepare the endometrium for the implantation of a fertilized egg. During pregnancy, it is secreted by the placenta to prevent spontaneous abortion and to stimulate the development of mammary tissue to produce milk. Thus, progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy. Luteinized theca cells of normal ovary secrete progesterone. The determination of progesterone concentrations in the body fluids is of great value for endocrinological investigations in women. This MAb may prove useful in identification of ovarian tumors.
Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. See the CF® Dye Selection Guide for more information. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. |
Informations produit
Purchasing Information | |
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Certification | RUO |
French code (NACRES) | NA.45 |
UNSPSC code | 41105331 |
EU customs code | 30021010 |
Human origin | No |
Target Details | |
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MW target protein (kDa) | 314.46Da |
Brand | |
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Brand | Biotium |
Product properties | |
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Supplier category 1 | Primary |
Clonality | Monoclonal |
Clone | 6-5E-3F |
Concentration | 0.1 mg/mL |
Conjugate / tag | Alkaline phosphatase |
Host | Mouse |
Immunogen | Progesterone hemisuccinate conjugated to bovine serum albumin |
isotype (antibody class) | IgG1, kappa |
Technical presentation | https://biotium.com/product/monoclonal-anti-progesterone-6-5e-3f |
Validated reactivity | All species |
Usage | |
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Shelf-Life (months) | 24 |
Shipping temperature | Room temperature |
Dilution for application | Immunohistology Not assessed |
Storage temperature | 2-8°C |
Applications | RIA (Radioactive Immuno Assay) |
Research area | Endocrinology |