Rabbit anti-mTOR Ab, Affinity Purified

Expédié par OZYME

Type SKU Price HT Quantity
  • 100 μl (1 mg/ml)
BETA300-504A
  • 100 μl (10 blots)
BETA300-504A-M
  • 20 μl (2 blots)
BETA300-504A-T

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General Information
Description Studies of the mammalian target of rapamycin (mTOR) and its homologs demonstrate a role in integrating signals from growth factors, nutrients, stress, and cellular energy levels to control cell growth, translation initiation, ribosome biogenesis, and transcription factor localization. mTOR is the direct target of the cell cycle arresting activity of rapamycin. mTOR interacts with Raptor or Rictor to form the mTORC1 and mTORC2 complexes respectively. The mTORC1 complex also includes mLst8/GbetaL and functions to phosphorylate S6K and 4EBP1. The mTORC2 complex also includes mLst8/GbetaL, mSIN1 and protor-1 and functions to phosphorylate Akt.

Informations produit

Purchasing Information
Certification RUO
French code (NACRES) NA.41
UNSPSC code 12352203
Country of origin (manufacturing) US
EU customs code 30021010
Vendor country US
Human origin No
Target Details
Other names FK506 binding protein 12-rapamycin associated protein 2, FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, FKBP12-rapamycin complex-associated protein 1, FKBP-rapamycin associated protein, FRAP, FRAP1, FRAP2, mammalian target of rapamycin, Mechanistic target of rapamycin, mechanistic target of rapamycin (serine/threonine kinase), mTOR, RAFT1, rapamycin and FKBP12 target 1, rapamycin associated protein FRAP2, rapamycin target protein 1, RAPT1, serine/threonine-protein kinase mTOR, SKS
Immunogen sequence between 200 and 250
Identification
NCBI (gene ID) 2475
Uniprot P42345
Brand
Brand Bethyl Laboratories
Product properties
Supplier category 2 Primary Antibodies
Supplier category 1 Primary Antibodies
Cross-reactivity Mouse , Rat
Type of Ig Whole molecule IgG (H+L)
MSDS https://www.bethyl.com/product/sds/A300-504A_SDS.pdf
Supplier category 3 PAB
Datasheet/manual https://www.bethyl.com/content/protocols
Marketing brochures https://www.bethyl.com/content/resources
Videos - tutorials https://yris.ozyme.fr/bet-video-tuto
Clonality Polyclonal
Conjugate / tag non conjugated
Host Rabbit
Immunogen between 200 and 250
isotype (antibody class) IgG
Validated reactivity Human
Technical presentation http://www.bethyl.com/product/A300-504A
Recombinant antibodies No
Usage
Shelf-Life (months) 12
Shipping temperature +4°C
Storage temperature +4°C
Applications WB (Western Blot) , IP ( Immuno Precipitation)

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