Rabbit anti-RPA70 IHC Ab, Affinity Purified

Expédié par OZYME

Conditionnement SKU Prix HT Quantité
  • 100 μl (50+ slides)
2-5
BETIHC-00409
  • 10 μl (5+ slides)
2-5
BETIHC-00409-T

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General Information
Description

Replication protein A (RPA) is a multisubunit complex that carries out DNA mismatch repair (MMR) in association with MSH2 (a subunit of human MutS heterodimers), MLH1 (a subunit of human MutL heterodimers), PCNA, and DNA polymerase-delta. RPA is composed of a heterotrimer that includes subunits of 70 kDa (RPA1), 32kDa (RPA2), and 14kDa (RPA3). RPA1, the 70 kDa subunit, is an ssDNA binding protein that has been shown to be phosphorylated by ATM and ATR in response to DNA damage. In addition to a role in MMR, RPA also functions in the initiation of DNA replication and DNA unwinding at origins of replication.

Informations produit

Purchasing Information
Certification RUO
French code (NACRES) NA.41
UNSPSC code 12352203
Country of origin (manufacturing) US
EU customs code 30021010
Vendor country US
Human origin No
Target Details
Other names HSSB, MST075, MSTP075, REPA1, replication factor A protein 1, replication protein A 70 kDa DNA-binding subunit, replication protein A1, 70kDa, RF-A, RF-A protein 1, RP-A, RP-A p70, RPA70, single-stranded DNA-binding protein
Immunogen sequence Between 350 and 400
Identification
NCBI (gene ID) 6117
Uniprot P27694
Brand
Brand Bethyl Laboratories
Product properties
Supplier category 1 Primary Antibodies
Videos - tutorials https://yris.ozyme.fr/bet-video-tuto
Marketing brochures https://www.bethyl.com/content/resources
Datasheet/manual https://www.bethyl.com/content/protocols
Supplier category 3 PAB
MSDS https://www.bethyl.com/product/sds/IHC-409_SDS.pdf
Supplier category 2 Primary Antibodies
Cross-reactivity Gray short-tailed opossum , Crab-eating macaque , Northern white-cheeked gibbon , Gorilla , Orangutan , Monkey , Chimpanzee , Rabbit
Type of Ig Whole molecule IgG (H+L)
Clonality Polyclonal
Conjugate / tag non conjugated
Host Rabbit
Special format Concentrated
Immunogen Between 350 and 400
isotype (antibody class) IgG
Technical presentation http://www.bethyl.com/product/IHC-409
Validated reactivity Human , Mouse
Recombinant antibodies No
Usage
Shelf-Life (months) 12
Shipping temperature +4°C
Storage temperature +4°C
Applications IHC (ImmunoHistoChemistry)

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